Tg(Cela1-Lta,Cela1-Ltb)58Heizu
Transgene Detail

Summary

• Symbol: Tg(Cela1-Lta,Cela1-Ltb)58Heizu
• Name: transgene insertion 58, Mathias Heikenwlder
• MGI ID: MGI:6506371
• Synonyms: Tg(Ela1-Lta,b)
• Transgene: Tg(Cela1-Lta,Cela1-Ltb)58Heizu Location: unknown
• Alliance: Tg(Cela1-Lta,Cela1-Ltb)58Heizu page

Transgene origin

• Strain of Origin: C57BL/6N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Cela1-Lta,Cela1-Ltb)58Heizu expresses 2 genes
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Lta (MGI:104797)
  mouse	Ltb (MGI:104796)

• Mutation details: Two transgenic constructs carrying mouse Lta and Ltb cDNA, respectively, under the control of the rat Cela1 (formerly Ela1) promoter are co-injected into C57BL/N zygotes. Founder lines 40 and 58 were established. Founder 58 is the high-expressing line. Southern blot analysis indicates that 3 copies of the transgene were integrated in the mouse genome. (J:301576)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:301576 Seleznik GM, et al., Lymphotoxin beta receptor signaling promotes development of autoimmune pancreatitis. Gastroenterology. 2012 Nov;143(5):1361-1374
• All: 2 reference(s)