Tg(ACTA1-Atf6)3Jmol
Transgene Detail

Summary

• Symbol: Tg(ACTA1-Atf6)3Jmol
• Name: transgene insertion 3, Jeffery Molkentin
• MGI ID: MGI:6505473
• Synonyms: ATF6alpha Tg
• Transgene: Tg(ACTA1-Atf6)3Jmol Location: unknown
• Alliance: Tg(ACTA1-Atf6)3Jmol page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(ACTA1-Atf6)3Jmol expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Atf6 (MGI:1926157)

• Mutation details: The transgenic vector contains a modified human ACTA1 promoter driving expression of full-length mouse Atf6 cDNA. The modified promoter incorporates 2 kb of 5' flanking sequence, 90 bases of 5'-UTR, and 149 bases of IVS1 (intervening sequence 1) from the human ACTA1 gene. This is founder line 3. (J:238094)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:238094 Vanhoutte D, et al., Thrombospondin expression in myofibers stabilizes muscle membranes. Elife. 2016 Sep 26;5:e17589
• All: 1 reference(s)