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Syisl Gene Detail
Summary
  • Symbol
    Syisl
  • Name
    Synpo2 intron sense-overlapping lncRNA
  • Feature Type
    sense intronic lncRNA gene
  • IDs
    MGI:6473178
    NCBI Gene: 141445974
  • Alliance
    gene page
Location &
Maps
less
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 3, Syntenic
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit increased muscle fiber density and muscle mass, improved muscle regeneration following injury and increased myogenic differentiation of myoblasts.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    52
  • Tissues
    44
  • cDNA Data
    2
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    Sequences &
    Gene Models
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    • All Sequences
      1
    Representative SequencesLengthStrain/SpeciesFlank
    transcript AK004418 GenBank | ENA | DDBJ | MGI Sequence Detail 1181 C57BL/6J  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 2
      cDNA 2
    References
    more
    • Summaries
      All 7
      Developmental Gene Expression 2
      Phenotypes 2
    • Earliest
      J:171050 Thiagarajan RD, et al., Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways. PLoS One. 2011;6(2):e17286
    • Latest
      J:362374 Zuo H, et al., SYISL Knockout Promotes Embryonic Muscle Development of Offspring by Modulating Maternal Gut Microbiota and Fetal Myogenic Cell Dynamics. Adv Sci (Weinh). 2025 Feb;12(6):e2410953
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/07/2026
    MGI 6.24     		The Jackson Laboratory