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Tg(IL1B-luc)1Smoc
Transgene Detail
Summary
Symbol: Tg(IL1B-luc)1Smoc
Name: transgene insertion 1, Shanghai Model Organisms Center
MGI ID: MGI:6431071
Synonyms: Tg(cHS4I-hIL-1betaP-Luc)Xen, Tg(IL1B-luc)Smoc
Transgene: Tg(IL1B-luc)1Smoc  Location: unknown  
Alliance: Tg(IL1B-luc)1Smoc page
Transgene
origin
Strain of Origin:  C57BL/6 x CBA
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsA 4.5-kb 5' flanking promoter region of the human IL-1beta drives expression of firefly luciferase cDNA. A chicken HS4 insulator (cHS4I) sequence was cloned upstream of the promoter to shield any effect of the chromosomal insertion site on transgene expression. (J:288206)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:288206 Li L, et al., Functional imaging of interleukin 1 beta expression in inflammatory process using bioluminescence imaging in transgenic mice. BMC Immunol. 2008 Aug 19;9:49
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory