Tg(Syn1-ATP6AP2)57994-1Yfeng
Transgene Detail

Summary

• Symbol: Tg(Syn1-ATP6AP2)57994-1Yfeng
• Name: transgene insertion 57994-1, Yumei Feng
• MGI ID: MGI:6404428
• Synonyms: Syn-hPRR
• Transgene: Tg(Syn1-ATP6AP2)57994-1Yfeng Location: unknown
• Alliance: Tg(Syn1-ATP6AP2)57994-1Yfeng page

Transgene origin

• Strain of Origin: (C57BL/6J x SJL/J)F2

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Syn1-ATP6AP2)57994-1Yfeng expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ATP6AP2 (10159)

  Atp6ap2

  (MGI:1917745)

• Full length human ATP6AP2/PRR cDNA is expressed from the rat Syn1 promoter. (J:258923)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:258923 Peng H, et al., Overexpression of the neuronal human (pro)renin receptor mediates angiotensin II-independent blood pressure regulation in the central nervous system. Am J Physiol Heart Circ Physiol. 2018 Mar 1;314(3):H580-H592
• All: 1 reference(s)