Tg(Thy1-DsRed2*,EGFP)27Kkuch
Transgene Detail

Summary

• Symbol: Tg(Thy1-DsRed2*,EGFP)27Kkuch
• Name: transgene insertion 27, Krzysztof Kucharz
• MGI ID: MGI:6401417
• Synonyms: Thy1-RedER
• Transgene: Tg(Thy1-DsRed2*,EGFP)27Kkuch Location: unknown
• Alliance: Tg(Thy1-DsRed2*,EGFP)27Kkuch page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The transgenic construct contains a modified DsRed2-IRES2-EGFP under the control of the mouse Thy1 (thymus cell antigen 1, theta) gene promoter. DsRed2 is flanked by an endoplasmic reticulum (ER) targeting sequence and a KDEL ER retention signal that targets fluorescent expression to the neuronal ER. The EGFP is expressed in the cytoplasm. Founder line 27 was established. (J:285988)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:285988 Kucharz K, et al., NMDA receptor stimulation induces reversible fission of the neuronal endoplasmic reticulum. PLoS One. 2009;4(4):e5250
• All: 1 reference(s)