Tg(Nr4a1-RFP)1Ayr
Transgene Detail

Summary

• Symbol: Tg(Nr4a1-RFP)1Ayr
• Name: transgene insertion 1, Alexander Y Rudensky
• MGI ID: MGI:6400467
• Synonyms: Nur77^RFP
• Transgene: Tg(Nr4a1-RFP)1Ayr Location: unknown
• Alliance: Tg(Nr4a1-RFP)1Ayr page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The BAC transgenic vector used to make this allele was adapted from the vector used to create Tg(Nr4a1-EGFP/cre)820Khog. The original transgenic vector was made by introducing a cre recombinase/green fluorescent protein (GFP) fusion cassette to the 5'end of the full-length Nr4a1 gene encoded by bacterial artificial chromosome (BAC) clone RP24-366J14. In this allele, the EGFP/cre fusion was replaced with turboRFP. (J:282187)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:282187 Hemmers S, et al., IL-2 production by self-reactive CD4 thymocytes scales regulatory T cell generation in the thymus. J Exp Med. 2019 Nov 4;216(11):2466-2478
• All: 1 reference(s)