Tg(Tff3/MUC5B)208Jlcd
Transgene Detail

Summary

• Symbol: Tg(Tff3/MUC5B)208Jlcd
• Name: transgene insertion 208, Jean-Luc Desseyn
• MGI ID: MGI:6357965
• Synonyms: K208, Tg208, Tg(Tff3/MUC5B)1Jlcd
• Transgene: Tg(Tff3/MUC5B)208Jlcd Location: unknown
• Alliance: Tg(Tff3/MUC5B)208Jlcd page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The mouse promoter with exons 1 and 2 are followed by an artificial exon 3 encoding 12 copies of the CYS domain#4 of the human MUC5B gene followed by a 3' end sequence. (J:82809, J:291183)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:291183 Gouyer V, et al., Delivery of a mucin domain enriched in cysteine residues strengthens the intestinal mucous barrier. Sci Rep. 2015 May 14;5:9577
• All: 2 reference(s)