Tg(tetO-luc,-Acot7)F26Rttr
Transgene Detail

Summary

• Symbol: Tg(tetO-luc,-Acot7)F26Rttr
• Name: transgene insertion F26, Guy Rutter
• MGI ID: MGI:6343537
• Synonyms: Acot7 Tg line F26
• Transgene: Tg(tetO-luc,-Acot7)F26Rttr Location: unknown
• Alliance: Tg(tetO-luc,-Acot7)F26Rttr page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence, Reporter)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: A bidirectional tetracycline-regulated promoter drives expression of a firefly luciferase reporter gene and FLAG-tagged murine cDNA. Lines F9, F26, and F15 were generated with 4, 7, and 70 copies of the transgene, respectively. (J:246783)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:246783 Martinez-Sanchez A, et al., Disallowance of Acot7 in beta-Cells Is Required for Normal Glucose Tolerance and Insulin Secretion. Diabetes. 2016 May;65(5):1268-82
• All: 1 reference(s)