Tg(Tph2-tTA)1Ahky
Transgene Detail
|
|
| Symbol: |
Tg(Tph2-tTA)1Ahky |
| Name: |
transgene insertion 1, Akihiro Yamanaka |
| MGI ID: |
MGI:6317248 |
| Transgene: |
Tg(Tph2-tTA)1Ahky Location: unknown
|
| Alliance: |
Tg(Tph2-tTA)1Ahky page
|
|
| Strain of Origin: |
CBA x C57BL/6
|
|
| Transgene Type: |
|
Transgenic (Transactivator) |
| Mutation: |
|
Insertion
|
| |
|
Mutation details: A cassette containing mammalianized tTA-SV40 polyadenylation signal-FRT-Neo-FRT was inserted into the translation initiation site of a BAC (clone RP23-112F24) carrying the Tph2 gene. Three founder mice were obtained (lines 6, 102, 108). Lines 102 and 108 exhibit ectopic mtTA mRNA expressions in the hippocampus and the dorsal cortex, but line 6 does not.
(J:276539)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
|
|
| Original: |
J:276539 Ohmura Y, et al., Optogenetic activation of serotonergic neurons enhances anxiety-like behaviour in mice. Int J Neuropsychopharmacol. 2014 Nov;17(11):1777-83 |
| All: |
15 reference(s) |
|
Analysis Tools
