Tg(tetO-SOX9)1Xy
Transgene Detail

Summary

• Symbol: Tg(tetO-SOX9)1Xy
• Name: transgene insertion 1, Xin Yuan
• MGI ID: MGI:6315862
• Transgene: Tg(tetO-SOX9)1Xy Location: unknown Genetic Position: ChrX, Syntenic
• Alliance: Tg(tetO-SOX9)1Xy page

Transgene origin

• Strain of Origin: FVB/NCrl

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO-SOX9)1Xy expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SOX9 (6662)

  Sox9	(MGI:98371)

• Mutation details: The 1.8kb transgenic construct contains a FLAG-tagged human Sox9 cDNA and an SV40 polyadenylation signal driven by the tetracycline operator (tetO). The transgene inserted on the X chromosome. (J:196713)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:196713 Wang H, et al., SOX9 regulates low density lipoprotein receptor-related protein 6 (LRP6) and T-cell factor 4 (TCF4) expression and Wnt/beta-catenin activation in breast cancer. J Biol Chem. 2013 Mar 1;288(9):6478-87
• All: 1 reference(s)