Tg(Astl/mCherry)1Dean
Transgene Detail

Summary

• Symbol: Tg(Astl/mCherry)1Dean
• Name: transgene insertion 1, Jurrien Dean
• MGI ID: MGI:6143842
• Synonyms: Astl^mCherry, ovastacin^mCherry, Tg(Astl-mCherry)1Dean
• Transgene: Tg(Astl/mCherry)1Dean Location: unknown
• Alliance: Tg(Astl/mCherry)1Dean page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: A bacterial artificial chromosome (BAC) DNA (Life Technologies) that included mouse Astl (BMQ56H22) was used to construct the transgene. These mice express ovastacin tagged with fluorescent mCherry at the C-terminus under the control of the endogenous Astl promoter. (J:239512)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:239512 Xiong B, et al., A Unique Egg Cortical Granule Localization Motif Is Required for Ovastacin Sequestration to Prevent Premature ZP2 Cleavage and Ensure Female Fertility in Mice. PLoS Genet. 2017 Jan;13(1):e1006580
• All: 2 reference(s)