Tg(Myl1-rtTA2S*M2)1Lach
Transgene Detail
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Symbol: |
Tg(Myl1-rtTA2S*M2)1Lach |
Name: |
transgene insertion 1, Lewis A Chodosh |
MGI ID: |
MGI:6117323 |
Synonyms: |
MDAFrtTA |
Transgene: |
Tg(Myl1-rtTA2S*M2)1Lach Location: unknown
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Alliance: |
Tg(Myl1-rtTA2S*M2)1Lach page
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Strain of Origin: |
C57BL/6 x DBA
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Transgene Type: |
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Transgenic (Transactivator) |
Mutation: |
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Insertion
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Mutation details: The modified reverse tetracycline transactivator (rtTA) with an increased doxycycline sensitivity and lower basal activity (rtTA2S-M2) is expressed under the control of the rat myosin light chain 1 gene promoter and MLC1/3 enhancer. Expression is seen in skeletal muscle. Two lines were generated, with one studied further.
(J:106884)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 2 strains available
Cell Lines: 0 lines available
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Original: |
J:106884 Ponomareva ON, et al., Defective neuromuscular synaptogenesis in mice expressing constitutively active ErbB2 in skeletal muscle fibers. Mol Cell Neurosci. 2006 Feb;31(2):334-45 |
All: |
5 reference(s) |
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