Rr46 Other Genome Feature Detail

Summary

• Symbol
  Rr46
• Name
  regulatory region 46
• Synonyms
  Macs1

• Feature Type
  enhancer
• IDs
  MGI:6117282
• Regulates expression of
  Shh (1 regulated gene)

Location &
Maps

• Sequence Map
  Chr5:29416520-29418073 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 5, Syntenic

Strain
Comparison

• SNPs within 2kb
  78 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotype references
  

• All Mutations and Alleles
  2
• Targeted
  2
• Genomic Mutations
  1 involving Rr46
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 3

  Phenotypes 2
• Earliest
  J:231964 Yao Y, et al., Cis-regulatory architecture of a brain signaling center predates the origin of chordates. Nat Genet. 2016 May;48(5):575-80
• Latest
  J:244162 Sagai T, et al., Evolution of Shh endoderm enhancers during morphological transition from ventral lungs to dorsal gas bladder. Nat Commun. 2017 Feb 03;8:14300

Rr46 regulates expression of:

Feature	Feature Type	Location	Reference
Shh, sonic hedgehog	protein coding gene	Chr5:28661838-28672099 (-)	J:244162