Tg(Acta2-DsRed)1Rkl
Transgene Detail

Summary

• Symbol: Tg(Acta2-DsRed)1Rkl
• Name: transgene insertion 1, Raghu Kalluri
• MGI ID: MGI:6100938
• Synonyms: alphaSMA-RFP
• Transgene: Tg(Acta2-DsRed)1Rkl Location: unknown
• Alliance: Tg(Acta2-DsRed)1Rkl page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The transgenic construct containsa DsRed-Express protein sequence followed by three SV40 polyadenylation signals (from pDsRed-Express-1 (Clontech)) under control of an extended 5.2kb mouse Acta2 (actin, alpha 2, smooth muscle, aorta) gene promoter that includes the Acta2 promoter plus exon 1, intron 1, and part of exon 2. (J:249881)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:249881 LeBleu VS, et al., Identification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosis. Nat Med. 2013 Feb;19(2):227-31
• All: 12 reference(s)