Tg(SV40-HA*)HA28Ajca
Transgene Detail

Summary

• Symbol: Tg(SV40-HA*)HA28Ajca
• Name: transgene insertion HA28, Andrew J Caton
• MGI ID: MGI:6095184
• Synonyms: HA28
• Transgene: Tg(SV40-HA*)HA28Ajca Location: unknown
• Alliance: Tg(SV40-HA*)HA28Ajca page

Transgene origin

• Strain of Origin: BALB/c x C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The transgene contains a single base deletion that causes a frameshift and results in expression of a polypeptide containing the N-terminal signal sequence plus amino acids 1-237 of PR8 hemagglutinin (HA) driven by the SV40 early region promoter-enhancer and polyadenylation sequences. Two lineages were established, HA28 and HA37, with two to three transgene copies each. (J:137514)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:137514 Cerasoli DM, et al., Low avidity recognition of a class II-restricted neo-self peptide by virus-specific T cells. Int Immunol. 1995 Jun;7(6):935-45
• All: 5 reference(s)