Tg(LY96)7020Haj
Transgene Detail

Summary

• Symbol: Tg(LY96)7020Haj
• Name: transgene insertion 7020, Adeline Hajjar
• MGI ID: MGI:5911246
• Transgene: Tg(LY96)7020Haj Location: unknown Genetic Position: ChrY, Syntenic
• Alliance: Tg(LY96)7020Haj page

Transgene origin

• Strain of Origin: C3H or C57BL/6

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(LY96)7020Haj expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  LY96 (23643)

  Ly96	(MGI:1341909)

• Mutation details: The transgenewas designed with a human BAC RP11-592J7 containing the entire LY96 gene. Founder line 7020 was established and carries two copies of the transgene. The BAC contains at least 50 Kb of human genomic sequences flanking the gene. (J:194866)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

Notes

BAC DNA was microinjected into (C57BL/6 x C3H)F1 x C57BL/6 (B6C3 x C57BL/6) fertilized oocytes. (J:194866)

References

• Original: J:194866 Hajjar AM, et al., Humanized TLR4/MD-2 mice reveal LPS recognition differentially impacts susceptibility to Yersinia pestis and Salmonella enterica. PLoS Pathog. 2012;8(10):e1002963
• All: 2 reference(s)