Tg(Myh6/tetO-Rem1*)1Jmol
Transgene Detail

Summary

• Symbol: Tg(Myh6/tetO-Rem1*)1Jmol
• Name: transgene insertion 1, Jeffery Molkentin
• MGI ID: MGI:5897306
• Transgene: Tg(Myh6/tetO-Rem1*)1Jmol Location: unknown
• Alliance: Tg(Myh6/tetO-Rem1*)1Jmol page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: Mice bearing this transgene express truncated mouse Rem1 cDNA (rad and gem related GTP binding protein 1; an L-type Ca2+ channel (LTCC) inhibitor) cDNA corresponding to amino acids 1-265 fused at its amino terminal to the canonical caveolin binding domain (CBD; RNVPPIFNDVYWIAF) under the conditional control of the mouse Myh6 (myosin, heavy polypeptide 6, cardiac muscle, alpha) promoter and the tetracycline-responsive element (TRE or tetO). Carboxy-terminal truncation of the REM protein inhibits membrane association. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)