About   Help   FAQ
Tg(CAG-HSPB1)HPks
Transgene Detail
Summary
Symbol: Tg(CAG-HSPB1)HPks
Name: transgene insertion H, Nick Parkinson
MGI ID: MGI:5775094
Synonyms: chk.actin-HSP27 (WT), HSP27 WT High copy line, PCAGGS-HSP27-WT-HIGH-COPY
Transgene: Tg(CAG-HSPB1)HPks  Location: unknown  
Alliance: Tg(CAG-HSPB1)HPks page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(CAG-HSPB1)HPks expresses 1 gene
 
Mutation detailsThe transgene comprises the coding sequence for wild-type human heat shock protein family B (small) member 1 (HSPB1) downstream of the "CAG promoter" -- which consists of the cytomegalovirus immediate early (CMV-EI) enhancer followed by a 1.3-kb DNA segment including the promoter, first exon and first intron of the chicken beta-actin gene, with the 3' splice junction sequence replaced by that of the rabbit hemoglobin beta gene -- and followed by the rabbit beta-hemoglobin polyadenylation signal and 3' flanking sequence. Heterozygous mice of this high copy number line carry approximately 35 copies of the transgene. (J:82809)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/21/2024
MGI 6.23
The Jackson Laboratory