Dp(16Mis18a-Runx1)2TybEmcf Cytogenetic Marker Detail

Summary

• Symbol
  Dp(16Mis18a-Runx1)2TybEmcf
• Name
  duplication, Chr 16, Victor Tybulewicz and Elizabeth M C Fisher 2

• Feature Type
  chromosomal duplication
• IDs
  MGI:5703854

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 16, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 1 genetic background
  4 phenotype references
  

• All Mutations and Alleles
  1
• Targeted
  1
• Find Mice (IMSR)
  2 strains or lines available

References

• Summaries
  All 4

  Phenotypes 4
• Earliest
  J:227899 Lana-Elola E, et al., Genetic dissection of Down syndrome-associated congenital heart defects using a new mouse mapping panel. Elife. 2016 Jan 14;5:e11614
• Latest
  J:335294 Redhead Y, et al., Craniofacial dysmorphology in Down syndrome is caused by increased dosage of Dyrk1a and at least three other genes. Development. 2023 Apr 15;150(8):dev201077