Tg(CAG-LEPROT)1Blll
Transgene Detail

Summary

• Symbol: Tg(CAG-LEPROT)1Blll
• Name: transgene insertion 1, Bernard Bailleul
• MGI ID: MGI:5648952
• Synonyms: LEPROT-Tg, Tg(CMV-ACTB/hLEPROT)
• Transgene: Tg(CAG-LEPROT)1Blll Location: unknown
• Alliance: Tg(CAG-LEPROT)1Blll page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-LEPROT)1Blll expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  LEPROT (54741)

  Leprot

  (MGI:2687005)

• Mutation details: The transgene is composed of the open reading frame of human LEPROT flanked by the cytomegalovirus enhancer, the chicken beta-actin promoter sequence, and the rabbit beta-globin polyadenylation sequence. One line was generated. (J:155099)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:155099 Touvier T, et al., LEPROT and LEPROTL1 cooperatively decrease hepatic growth hormone action in mice. J Clin Invest. 2009 Dec;119(12):3830-8
• All: 2 reference(s)