Tg(Cnp-TVA,-lacZ)B8Ubc
Transgene Detail
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Symbol: |
Tg(Cnp-TVA,-lacZ)B8Ubc |
Name: |
transgene insertion B8, Uppsala University |
MGI ID: |
MGI:5648077 |
Synonyms: |
Tg(Cnp-CD320,-lacZ)B8Ubc |
Transgene: |
Tg(Cnp-TVA,-lacZ)B8Ubc Location: unknown
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Alliance: |
Tg(Cnp-TVA,-lacZ)B8Ubc page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Mutation details: The transgenic construct contained the entire mouse Cnp promoter region coupled to the 800-bp quail cDNA encoding the glycosylphosphatidylinositol-linked form of TVA (CD320 or Tv-a) gene, the receptor for avian retrovirus ALV, subgroup A (ALV-A), followed by an IRES (internal ribosomal entry site) sequence and the lacZ gene. Pronuclear injection generated three chimera founders with germ-line transmission (A7, B8 and C16). After initial characterization for expression of TVA the B8 line was selected for further breeding.
(J:151346)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 4 strains available
Cell Lines: 0 lines available
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All were phenotypically normal, viable and fertile.
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Original: |
J:151346 Lindberg N, et al., Oligodendrocyte progenitor cells can act as cell of origin for experimental glioma. Oncogene. 2009 Jun 11;28(23):2266-75 |
All: |
3 reference(s) |
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