Del(2Duoxa2-Duoxa1)1Sref Cytogenetic Marker Detail

Summary

• Symbol
  Del(2Duoxa2-Duoxa1)1Sref
• Name
  deletion, Chr 2, Samuel Refetoff 1

• Feature Type
  chromosomal deletion
• IDs
  MGI:5583965

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 2, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  21 phenotypes from 1 allele in 1 genetic background
  11 phenotype references
  

• All Mutations and Alleles
  1
• Targeted
  1
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 11

  Phenotypes 11
• Earliest
  J:205329 Grasberger H, et al., Mice deficient in dual oxidase maturation factors are severely hypothyroid. Mol Endocrinol. 2012 Mar;26(3):481-92
• Latest
  J:334724 Duan J, et al., Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut. Immunity. 2023 Mar 7;