Tg(PECAM1-hir/CD4/SELP)#aAdor
Transgene Detail
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Symbol: |
Tg(PECAM1-hir/CD4/SELP)#aAdor |
Name: |
transgene insertion #a, Anthony Dorling |
MGI ID: |
MGI:5578128 |
Synonyms: |
CD31-Hir-Tg |
Transgene: |
Tg(PECAM1-hir/CD4/SELP)#aAdor Location: unknown
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Alliance: |
Tg(PECAM1-hir/CD4/SELP)#aAdor page
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Strain of Origin: |
Not Specified
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Mutation details: The human promoter drives expression of the fusion of leech hirudin, domains 3 and 4 of human CD4 domain and intracytoplasmic sequence of human SELP in endothelial cells, monocytes and platelets. Four founders were generated. The unnamed line (#a) contains greater than 30 copies of the transgene.
(J:92695)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 2 strains available
Cell Lines: 0 lines available
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Original: |
J:92695 Chen D, et al., Inhibition of intravascular thrombosis in murine endotoxemia by targeted expression of hirudin and tissue factor pathway inhibitor analogs to activated endothelium. Blood. 2004 Sep 1;104(5):1344-9 |
All: |
4 reference(s) |
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