Tg(H2-K-Cebpa)1Ipp
Transgene Detail

Summary

• Symbol: Tg(H2-K-Cebpa)1Ipp
• Name: transgene insertion 1, Ido Paz-Priel
• MGI ID: MGI:5576376
• Synonyms: H2K-C/EBPalpha-Emu, Tg(H2K^b-Cebpa)1Ipp
• Transgene: Tg(H2-K-Cebpa)1Ipp Location: unknown
• Alliance: Tg(H2-K-Cebpa)1Ipp page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(H2-K-Cebpa)1Ipp expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  rat

  Cebpa (24252)

  Cebpa

  (MGI:99480)

• Mutation details: The rat Cebpa cDNA was ligated downstream of the H2K^b promoter and upstream of a beta-globin genomic segment providing polyadenylic acid signals and the Emu immunoglobulin heavy chain enhancer. (J:211772)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:211772 Paz-Priel I, et al., CCAAT/enhancer binding protein alpha (C/EBPalpha) and C/EBPalpha myeloid oncoproteins induce bcl-2 via interaction of their basic regions with nuclear factor-kappaB p50. Mol Cancer Res. 2005 Oct;3(10):585-96
• All: 1 reference(s)