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Del(2Hoxd1-Hoxd9)63Ddu Cytogenetic Marker Detail
Summary
  • Symbol
    Del(2Hoxd1-Hoxd9)63Ddu
  • Name
    deletion, Chr 2, Denis Duboule 63
  • Feature Type
    chromosomal deletion
  • IDs
    MGI:5508533
Location &
Maps
more
  • Sequence Map
    Chr2:74528107-74595486 bp
    From MGI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, Syntenic
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice heterozygous for this deletion exhibit atypical female courtship behavior with female mice aggressively chasing males and biting their genitals.
References
more
  • Summaries
    All 4
    Phenotypes 3
  • Earliest
    J:199759 Zakany J, et al., A genetic basis for altered sexual behavior in mutant female mice. Curr Biol. 2012 Sep 25;22(18):1676-80
  • Latest
    J:259687 Zakany J, et al., Rescue of an aggressive female sexual courtship in mice by CRISPR/Cas9 secondary mutation in vivo. BMC Res Notes. 2018 Mar 27;11(1):193
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory