Sum2 Gene Detail

Summary

• Symbol
  Sum2
• Name
  suppressor of methyl CpG binding protein 2, 2

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:5489926
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr3:136077680-147596662 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 3, Syntenic
• Mapping Data
  1 experiment

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  7 phenotypes from multigenic genotypes
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Chemically induced (ENU)
  1
• Find Mice (IMSR)
  0 strains or lines available

Mice heterozygous for the mutation exhibit improved Rett syndrome phenotypes.

References

• Summaries
  All 2

  Phenotypes 1
• Earliest
  J:198551 Buchovecky CM, et al., A suppressor screen in Mecp2 mutant mice implicates cholesterol metabolism in Rett Syndrome. Nat Genet. 2013;45(9):1013-20