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Del(1Fmo4-Fmo2)1Eshe Cytogenetic Marker Detail
Summary
  • Symbol
    Del(1Fmo4-Fmo2)1Eshe
  • Name
    deletion, Chr 1, Elizabeth A Shephard 1
  • Synonyms
    Del(Fmo4-Fmo2)1Eshe
  • Feature Type
    chromosomal deletion
  • IDs
    MGI:5487816
Location &
Maps
less
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 1, Syntenic
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for this deletion exhibit enhanced behavioral response to imipramine and impaired imipramine oxidation.
References
more
  • Summaries
    All 5
    Phenotypes 4
  • Earliest
    J:196270 Hernandez D, et al., Deletion of the mouse Fmo1 gene results in enhanced pharmacological behavioural responses to imipramine. Pharmacogenet Genomics. 2009 Apr;19(4):289-99
  • Latest
    J:328499 Veeravalli S, et al., Flavin-Containing Monooxygenase 1 Catalyzes the Production of Taurine from Hypotaurine. Drug Metab Dispos. 2020 May;48(5):378-385

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory