Del(1Fcgr2b-Fcgr3)1Rav Cytogenetic Marker Detail

Summary

• Symbol
  Del(1Fcgr2b-Fcgr3)1Rav
• Name
  deletion, Chr 1, Jeffrey V Ravetch 1

• Feature Type
  chromosomal deletion
• IDs
  MGI:5426839

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 1, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from multigenic genotypes
  14 phenotype references
  

• All Mutations and Alleles
  1
• Targeted
  1
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 14

  Phenotypes 14
• Earliest
  J:183615 Smith P, et al., Mouse model recapitulating human Fcgamma receptor structural and functional diversity. Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6181-6
• Latest
  J:386149 Osorio JC, et al., Fc-optimized CD40 agonistic antibody elicits tertiary lymphoid structure formation and systemic antitumor immunity in metastatic cancer. Cancer Cell. 2025 Oct 13;43(10):1902-1916.e9