Del(1Fcgr2b-Fcgr3)1Rav Cytogenetic Marker Detail

Summary

• Symbol
  Del(1Fcgr2b-Fcgr3)1Rav
• Name
  deletion, Chr 1, Jeffrey V Ravetch 1

• Feature Type
  chromosomal deletion
• IDs
  MGI:5426839

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 1, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from multigenic genotypes
  13 phenotype references
  

• All Mutations and Alleles
  1
• Targeted
  1
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 13

  Phenotypes 13
• Earliest
  J:183615 Smith P, et al., Mouse model recapitulating human Fcgamma receptor structural and functional diversity. Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6181-6
• Latest
  J:370538 Blanchard L, et al., Fc-optimized anti-CTLA-4 antibodies increase tumor-associated high endothelial venules and sensitize refractory tumors to PD-1 blockade. Cell Rep Med. 2025 Jun 17;6(6):102141