Tg(TERT-rluc)DJzhu
Transgene Detail

Summary

• Symbol: Tg(TERT-rluc)DJzhu
• Name: transgene insertion D, Jiyue Zhu
• MGI ID: MGI:5318989
• Synonyms: hTERT-Renilla luciferase reporter
• Transgene: Tg(TERT-rluc)DJzhu Location: unknown
• Alliance: Tg(TERT-rluc)DJzhu page

Transgene origin

• Strain of Origin: FVB/NJ

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The 158 kb human bacterial artificial chromosome (BAC) RPCI11-117B23 containing CLPTM1L (CLPTM1-like), TERT (telomerase reverse transcriptase) and SLC6A18 (solute carrier family 6, member 18) genes, was modified by inserting a codon optimized Renilla reniformis luciferase ORF at the TERT ATG codon. The BAC vector may contain loxP/lox511 sequences. (J:182426)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:182426 Jia W, et al., A BAC transgenic reporter recapitulates in vivo regulation of human telomerase reverse transcriptase in development and tumorigenesis. FASEB J. 2011 Mar;25(3):979-89
• All: 1 reference(s)