Tg(Lck-AVEN)1Zrng
Transgene Detail

Summary

• Symbol: Tg(Lck-AVEN)1Zrng
• Name: transgene insertion 1, Martin Zoernig
• MGI ID: MGI:5317419
• Synonyms: Tg(Lck-Aven)
• Transgene: Tg(Lck-AVEN)1Zrng Location: unknown
• Alliance: Tg(Lck-AVEN)1Zrng page

Transgene origin

• Strain of Origin: CD-1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Lck-AVEN)1Zrng expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  AVEN (57099)

  Aven	(MGI:1921518)

• Mutation details: This transgene contains a full-length cDNA encoding human caspase activation inhibitor (AVEN) inserted into the p1017 expression vector, which contains a 3.2 kb fragment of the mouse lymphocyte protein tyrosine kinase (Lck) gene that includes its thymocyte-specific proximal promoter through nucleotide +37 (relative to the transcription initiation site) upstream of the nearly full-length human growth hormone (GH1) gene; the insertion site is in the truncated first exon of GH1, which encodes the 5' UTR. (J:82809, J:132210)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 3 reference(s)