Mirc23 Complex/Cluster/Region Detail

Summary

• Symbol
  Mirc23
• Name
  microRNA cluster 23, including Mir374b through Mir421

• Feature Type
  complex/cluster/region
• IDs
  MGI:5313580
• Cluster Members
  Mir421, Mir374b, Mir374c (3 members)

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome X, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 1 genetic background
  3 phenotype references
  

• All Mutations and Alleles
  3
• Endonuclease-mediated
  1
• Targeted
  2
• Find Mice (IMSR)
  1 strains or lines available

Mice homozygous or hemizygous for a knock-out allele exhibit normal eyes.

Other Database
Links

miRBase

MI0004125, MI0005496, MI0014108

References

• Summaries
  All 4

  Phenotypes 3
• Earliest
  J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
• Latest
  J:268562 Hosoi Y, et al., Female mice lacking Ftx lncRNA exhibit impaired X-chromosome inactivation and a microphthalmia-like phenotype. Nat Commun. 2018 Sep 20;9(1):3829

Mirc23 Cluster contains:

More Data for these features

Member	Feature Type	Location
Mir421, microRNA 421	miRNA gene	ChrX:102616527-102616602 (-)
Mir374b, microRNA 374b	miRNA gene	ChrX:102616666-102616760 (-)
Mir374c, microRNA 374c	miRNA gene	ChrX:102616691-102616739 (+)