Tg(Fos-tTA)1Mmay
Transgene Detail

Summary

• Symbol: Tg(Fos-tTA)1Mmay
• Name: transgene insertion 1, Mark Mayford
• MGI ID: MGI:5014071
• Transgene: Tg(Fos-tTA)1Mmay Location: unknown
• Alliance: Tg(Fos-tTA)1Mmay page

Transgene origin

• Strain of Origin: Not Specified
• Project Collection: Neuroscience Blueprint cre

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Mutation details: The c-fos-tTA transgene was designed with the promoter region from the mouse FBJ osteosarcoma oncogene (Fos or c-fos; at least 611 bp of 5' untranscribed sequence that encompasses the known mouse c-fos regulatory elements) placed upstream of the tetracycline-regulated transactivator gene (tTA or "Tet-Off" ; flanked by an artificial intron and splice sites at the 5' end and by a polyadenylation signal from SV40 at the 3' end). Specifically, the tTA was inserted into the AccI site of the first exon of the mouse c-fos gene, (J:151755)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:151755 NIH Neuroscience Blueprint Cre Driver Network, Cre recombinase-expressing mice generated for the NIH Neuroscience Blueprint Cre Driver Network. MGI Direct Data Submission. 2009
• All: 17 reference(s)