Tg(Myh6/tetO-Gata4)1Jmol
Transgene Detail

Summary

• Symbol: Tg(Myh6/tetO-Gata4)1Jmol
• Name: transgene insertion 1, Jeffery D Molkentin
• MGI ID: MGI:5002502
• Transgene: Tg(Myh6/tetO-Gata4)1Jmol Location: unknown
• Alliance: Tg(Myh6/tetO-Gata4)1Jmol page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(Myh6/tetO-Gata4)1Jmol expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Gata4 (MGI:95664)

• Mutation details: These Gata4 transgenic mice contains the GATA binding protein 4 (Gata4) sequence regulated by a tetracycline operator (tetO), driven by myosin, heavy polypeptide 6, cardiac muscle, alpha (Myh6 or alpha-MHC) promoter/enhancer elements. Line 1 was generated. (J:127378)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:127378 Heineke J, et al., Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart. J Clin Invest. 2007 Nov;117(11):3198-210
• All: 1 reference(s)