Tg(S100a4-EGFP)M1Egn
Transgene Detail

Summary

• Symbol: Tg(S100a4-EGFP)M1Egn
• Name: transgene insertion M1, Eric G Neilson
• MGI ID: MGI:4819359
• Synonyms: FSP1.gfp, Tg(Fsp1-GFP)
• Transgene: Tg(S100a4-EGFP)M1Egn Location: unknown
• Alliance: Tg(S100a4-EGFP)M1Egn page

Transgene origin

• Strain of Origin: C57BL/6 x DBA/2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The transgenic construct containing sequence encoding EGFP under the control of the mouse S100a4, S100 calcium binding protein A4, promoter. These transgenic mice express GFP under the control of the mouse S100a4, S100 calcium binding protein A4, promoter. All tissue fibroblasts in adult hemizygous mice fluoresce. Woods light examination of the eyes of adult transgenic mice reveal green fluorescence of the fibroblasts of the cornea. Green fluorescing fibroblasts are detected in kidney, liver, lung and heart and occasionally in interstitial organ spaces. Founder line M1 was established. (J:111660)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:111660 Iwano M, et al., Evidence that fibroblasts derive from epithelium during tissue fibrosis. J Clin Invest. 2002 Aug;110(3):341-50
• All: 18 reference(s)