Tg(GPD1*)124ABir
Transgene Detail

Summary

• Symbol: Tg(GPD1*)124ABir
• Name: transgene insertion 124A, Edward H Birkenmeier
• MGI ID: MGI:3799699
• Synonyms: FSE d124A, Tg(FSE124A)17Bir
• Transgene: Tg(GPD1*)124ABir Location: unknown
• Alliance: Tg(GPD1*)124ABir page

Transgene origin

• Strain of Origin: (C57BL/6J x SJL/J)F2

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(GPD1*)124ABir expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  GPD1 (2819)

  Gpd1	(MGI:95679)

• Mutation details: The transgenic construct encodes a deletion in fat-specific element(FSE)region of human GPD1 promoter (deletes from -258 to -135, or 124 bp). A second strain, d124B, was also created (2-5 copies in each) and two shorter deletion (36 bp) mutants (d36A, d36B) were generated. (J:135002)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:135002 Birkenmeier EH, et al., Tissue- and cell-specific expression of human sn-glycerol-3-phosphate dehydrogenase in transgenic mice. Nucleic Acids Res. 1992 Jun 11;20(11):2819-25
• All: 1 reference(s)