Tg(TcraBM3.3,TcrbBM3.3)1Alm
Transgene Detail

Summary

• Symbol: Tg(TcraBM3.3,TcrbBM3.3)1Alm
• Name: transgene insertion 1, Andrew L Mellor
• MGI ID: MGI:3793487
• Synonyms: BM3, BM3.6, BM3 TCR-transgenic
• Transgene: Tg(TcraBM3.3,TcrbBM3.3)1Alm Location: unknown
• Alliance: Tg(TcraBM3.3,TcrbBM3.3)1Alm page

Transgene origin

• Strain of Origin: CBA

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(TcraBM3.3,TcrbBM3.3)1Alm expresses 2 genes
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Tcra (MGI:98553)
  mouse	Tcrb (MGI:98578)

• Mutation details: TCR transgenic mice were generated by injecting fertilized oocytes with DNA constructs containing productively rearranged recombinant TCR alpha and beta genes derived from the H-2Kb specific CTL clone BM3.3. (J:113712, J:133605)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:113712 Sponaas AM, et al., Induction of tolerance to self MHC class I molecules expressed under the control of milk protein or beta-globin gene promoters. Int Immunol. 1994 Feb;6(2):277-87
• All: 13 reference(s)