Del(5Cyp3a57-Cyp3a59)2Nki Cytogenetic Marker Detail

Summary

• Symbol
  Del(5Cyp3a57-Cyp3a59)2Nki
• Name
  deletion, Chr 5, The Netherlands Cancer Institute 2
• Synonyms
  Del1Ahs, Del(5Cyp3a57-Cyp3a59)1Ahs

• Feature Type
  chromosomal deletion
• IDs
  MGI:3775603

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 5, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 1 genetic background
  3 phenotypes from multigenic genotypes
  4 phenotype references
  

• All Mutations and Alleles
  1
• Targeted
  1
• Find Mice (IMSR)
  0 strains or lines available

Other
Accession IDs

MGI:6452218

References

• Summaries
  All 5

  Phenotypes 4
• Earliest
  J:127366 van Herwaarden AE, et al., Knockout of cytochrome P450 3A yields new mouse models for understanding xenobiotic metabolism. J Clin Invest. 2007 Nov;117(11):3583-92
• Latest
  J:385908 Roichman A, et al., Microbiome metabolism of dietary phytochemicals controls the anticancer activity of PI3K inhibitors. Cell. 2025 May 29;188(11):3065-3080.e21