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cosa Gene Detail
Summary
  • Symbol
    cosa
  • Name
    cochleo-saccular defects
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:3665146
  • Alliance
Location &
Maps
less
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome Unknown
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for this mutation are hyperactive, exhibit head shaking and circling behavior, lack startle response to sound, cannot swim, and have abnormal cochlear morphology.
References
more
  • Summaries
    All 1
    Phenotypes 1
  • Earliest
    J:113137 Oda S, et al., A new mouse model with cochleo-saccular type inner ear defects. Exp Anim. 2001 Oct;50(5):417-21

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory