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repro3 Gene Detail
Summary
  • Symbol
    repro3
  • Name
    reproductive mutation 3, JAX Reproductive Mutagenesis Program
  • Synonyms
    G1-397-28
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:3590178
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr10:44021933-46720483 bp
    From MGI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, Syntenic
  • Mapping Data
    1 experiment
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygotes for this ENU-induced mutation exhibit male reproductive abnormalities including infertility, low sperm concentration, abnormal sperm head and tail morphology, no sperm motility, and inability of sperm to fertilize oocytes.
References
more
  • Summaries
    All 2
    Phenotypes 1
  • Earliest
    J:117563 Lessard C, et al., Mutagenesis-generated mouse models of human infertility with abnormal sperm. Hum Reprod. 2007 Jan;22(1):159-66
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory