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tmgc46 Gene Detail
Summary
  • Symbol
    tmgc46
  • Name
    Tennessee Mouse Genome Consortium 46
  • Synonyms
    118TNE
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:3589214
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 16, Syntenic
  • Mapping Data
    2 experiments
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygotes for this ENU-induced mutation exhibit high frequency hearing loss, with absent brainstem auditory evoked potential at 32kHz and decreased brainstem auditory evoked potential at 8 and 16KHz.
References
more
  • Summaries
    All 4
    Phenotypes 3
  • Earliest
    J:112370 Habiby Kermany M, et al., Identification of 17 hearing impaired mouse strains in the TMGC ENU-mutagenesis screen. Hear Res. 2006 Oct;220(1-2):76-86
  • Latest
    J:166103 Jiao Y, et al., ENU induced single mutation locus on chr 16 leads to high-frequency hearing loss in mice. Genes Genet Syst. 2009 Jun;84(3):219-24
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory