Tg(TTR-GLVP)1074Tsa
Transgene Detail

Summary

• Symbol: Tg(TTR-GLVP)1074Tsa
• Name: transgene insertion 1074, Sophia Y Tsai
• MGI ID: MGI:3056688
• Synonyms: TTR-GLVP
• Transgene: Tg(TTR-GLVP)1074Tsa Location: unknown
• Alliance: Tg(TTR-GLVP)1074Tsa page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(TTR-GLVP)1074Tsa expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  PGR (5241)

  Pgr	(MGI:97567)

• Mutation details: The transgene construct includes insulator DNA segments (5' region of chicken beta globin gene) flanking both ends of the GLVP transactivator which is driven by the transthyretin enhancer/promoter. The GLVP portion consists of a mutated human progesterone receptor ligand binding domain fused to the yeast GAL4 DNA binding domain and the HSV VP16 transcriptional activation domain. (J:93246)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

Notes

Transgenic mice display no phenotypic effects.

References

• Original: J:93246 Wang Y, et al., Ligand-inducible and liver-specific target gene expression in transgenic mice. Nat Biotechnol. 1997 Apr;15(3):239-43
• All: 3 reference(s)