Tg(Wnt1-lacZ)206Amc
Transgene Detail

Summary

• Symbol: Tg(Wnt1-lacZ)206Amc
• Name: transgene insertion 206, Andrew P McMahon
• MGI ID: MGI:3054869
• Synonyms: Tg(Rr695622-lacZ)206Amc, WZT9B
• Transgene: Tg(Wnt1-lacZ)206Amc Location: unknown
• Alliance: Tg(Wnt1-lacZ)206Amc page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details : The transgene contains 1.3 kb sequence from upstream of the Wnt1 translation start site (containing the promoter), a beta-galactosidase reporter gene cassette, and a 4.475 kb BglII restriction enzyme fragment from downstream of the Wnt1 poly(A) signal (containing enhancer Find Mice (IMSR):
  • Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
  • Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Notes:
  Transgenic mice on a mixed C57BL/6, CBA background show no phenotypic defects. LacZ is expressed in the dorsal CNS.
• References:
  • Original: J:19632 Echelard Y, et al., Cis-acting regulatory sequences governing Wnt-1 expression in the developing mouse CNS. Development. 1994 Aug;120(8):2213-24
  • All: 9 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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