Tg(CD2-Il2rg)1Ttg
Transgene Detail
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Symbol: |
Tg(CD2-Il2rg)1Ttg |
Name: |
transgene insertion 1, Tadatsugu Taniguchi |
MGI ID: |
MGI:3054416 |
Synonyms: |
IL-2Rg WT, Tg(Il2rg)WT |
Transgene: |
Tg(CD2-Il2rg)1Ttg Location: unknown
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Alliance: |
Tg(CD2-Il2rg)1Ttg page
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Strain of Origin: |
Not Specified
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(CD2-Il2rg)1Ttg expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Note |
mouse |
Il2rg (MGI:96551) |
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Mutation details: A cDNA encoding the full-length mouse interleukin 2 receptor gamma chain was inserted into an expression vector containing 5 kb of 5' flanking sequence, including the promoter, transcription initiation site and first intron, and 5.5 kb of 3' flanking sequence including the locus control region (LCR) of the human CD2 gene. The transgene product was found to be expressed on CD4+ CD8+ thymocytes and on splenic and peripheral blood T lymphocytes.
(J:92738)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:92738 Tsujino S, et al., Differential requirement of the cytoplasmic subregions of gamma c chain in T cell development and function. Proc Natl Acad Sci U S A. 2000 Sep 12;97(19):10514-9 |
All: |
1 reference(s) |
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