About   Help   FAQ
Tg(CD2-Il2rg)1Ttg
Transgene Detail
Summary
Symbol: Tg(CD2-Il2rg)1Ttg
Name: transgene insertion 1, Tadatsugu Taniguchi
MGI ID: MGI:3054416
Synonyms: IL-2Rg WT, Tg(Il2rg)WT
Transgene: Tg(CD2-Il2rg)1Ttg  Location: unknown  
Alliance: Tg(CD2-Il2rg)1Ttg page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(CD2-Il2rg)1Ttg expresses 1 gene
 
Mutation detailsA cDNA encoding the full-length mouse interleukin 2 receptor gamma chain was inserted into an expression vector containing 5 kb of 5' flanking sequence, including the promoter, transcription initiation site and first intron, and 5.5 kb of 3' flanking sequence including the locus control region (LCR) of the human CD2 gene. The transgene product was found to be expressed on CD4+ CD8+ thymocytes and on splenic and peripheral blood T lymphocytes. (J:92738)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:92738 Tsujino S, et al., Differential requirement of the cytoplasmic subregions of gamma c chain in T cell development and function. Proc Natl Acad Sci U S A. 2000 Sep 12;97(19):10514-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/21/2024
MGI 6.23
The Jackson Laboratory