Tg(Pax2-cre)1Akg
Transgene Detail
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Symbol: |
Tg(Pax2-cre)1Akg |
Name: |
transgene insertion 1, Andrew K Groves |
MGI ID: |
MGI:3046196 |
Synonyms: |
Pax2-Cre |
Transgene: |
Tg(Pax2-cre)1Akg Location: unknown
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Alliance: |
Tg(Pax2-cre)1Akg page
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Strain of Origin: |
Not Specified
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Transgene Type: |
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Transgenic (Recombinase) |
Mutation: |
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Insertion
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Tg(Pax2-cre)1Akg expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
Not Specified |
Pax2 |
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Mutation details: A 121kb segment of the Pax2 gene which included 101 kb of sequence upstream of exon1, all of exons 1 and 2, part of exon 3, as well as introns 1 and 2, was modified by the insertion of IRES-cre into exon 2. Cre expression was demonstrated in the otic placode starting at the 6-7 somite stage. Cre expression also occurred in the midbrain-hindbrain boundary and the embryonic kidney. Two founders showed germline transmission of cre, and the line that displayed stronger cre mRNA expression was designated by MGI as line 1.
(J:89784)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Pax2
(species not specified)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 2 strains available
Cell Lines: 0 lines available
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Original: |
J:89784 Ohyama T, et al., Generation of Pax2-Cre mice by modification of a Pax2 bacterial artificial chromosome. Genesis. 2004 Apr;38(4):195-9 |
All: |
123 reference(s) |
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