Tg(Trp53R193P)1Ber
Transgene Detail

Summary

• Symbol: Tg(Trp53R193P)1Ber
• Name: transgene insertion 1, Alan Bernstein
• MGI ID: MGI:3040382
• Synonyms: p53-1, Tg(p53)1Ber
• Transgene: Tg(Trp53R193P)1Ber Location: unknown
• Alliance: Tg(Trp53R193P)1Ber page

Transgene origin

• Strain of Origin: CD-1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Trp53R193P)1Ber expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Trp53 (MGI:98834)

• Mutation details: This transgene contains the mouse transformation related protein 53 promoter and an allele of the Trp53 gene that carries a point mutation in codon 193 (arginine to proline). (J:19870)

Tumor Data

List all tumor models in MMHCdb carrying Tg(Trp53R193P)1Ber

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Additional lines #2 and #3 were generated.

References

• Original: J:19870 Lavigueur A, et al., High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene. Mol Cell Biol. 1989 Sep;9(9):3982-91
• All: 1 reference(s)