Tg(TAg)11Bri
Transgene Detail

Summary

• Symbol: Tg(TAg)11Bri
• Name: transgene insertion 11, Ralph L Brinster
• MGI ID: MGI:2663945
• Synonyms: SV11, Tg(SV40-TAg)11Bri
• Transgene: Tg(TAg)11Bri Location: unknown
• Alliance: Tg(TAg)11Bri page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: This transgene contains the SV40 (simian virus 40) early gene promoter and the wild-type allele of the SV4 large T antigen gene (TAg). This pSV11 construct also contains the sequence for the SV40 enhancer region. (J:82816)

Tumor Data

List all tumor models in MMHCdb carrying Tg(TAg)11Bri

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

Notes

Transgene also called pSV11. Line 7 was also produced: see Tg(SV)7Bri .

References

• Original: J:53184 Palmiter RD, et al., SV40 enhancer and large-T antigen are instrumental in development of choroid plexus tumours in transgenic mice. Nature. 1985 Aug 1-7;316(6027):457-60
• All: 15 reference(s)