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Cigs2 Other Genome Feature Detail
Summary
  • Symbol
    Cigs2
  • Name
    conserved intergenic sequence 2
  • Synonyms
    GM-CSF enhancer region, HS5, HS V
  • Feature Type
    unclassified other genome feature
  • IDs
    MGI:1929205
    NCBI Gene: 64938
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 11, Syntenic
  • Mapping Data
    1 experiment
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    12 phenotypes from 2 alleles in 2 genetic backgrounds
    5 phenotypes from multigenic genotypes
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit abnormal interleukin secretion (Il4 and Il13), mast cell physiology, and neutrophil physiology.
Sequences &
Gene Models
less
  • All Sequences
    3
Representative SequencesLengthStrain/SpeciesFlank
genomic U47544 GenBank | ENA | DDBJ | MGI Sequence Detail 839 Not Specified ±  kb
For the selected sequence
References
more
  • Summaries
    All 10
    Phenotypes 5
  • Earliest
    J:26256 Osborne CS, et al., Transcriptional regulation of mouse granulocyte-macrophage colony-stimulating factor/IL-3 locus. J Immunol. 1995 Jul 1;155(1):226-35
  • Latest
    J:254605 Motomura Y, et al., Basophil-derived interleukin-4 controls the function of natural helper cells, a member of ILC2s, in lung inflammation. Immunity. 2014 May 15;40(5):758-71
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory