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Ear3 Gene Detail
Summary
  • Symbol
    Ear3
  • Name
    eosinophil-associated, ribonuclease A family, member 3
  • Synonyms
    mR3, murine ribonuclease 3, Rnase3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1858237
    NCBI Gene: 53876
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 14, Syntenic
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    RNASE2, ribonuclease A family member 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RNASE2, ribonuclease A family member 2
  • Synonyms
    EDN, RAF3, RNS2
  • Links
    NCBI Gene ID: 6036
    neXtProt AC: NX_P10153
    UniProt: P10153

  • Chr Location
    14q11.2; chr14:20955487-20956436 (+)  GRCh38
  • Human Ortholog
    RNASE3, ribonuclease A family member 3
  • Synonyms
    ECP, RAF1, RNS3
  • Links
    NCBI Gene ID: 6037
    neXtProt AC: NX_P12724
    UniProt: P12724

  • Chr Location
    14q11.2; chr14:20891385-20892348 (+)  GRCh38
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    10
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Other Mouse Links
    GEO
Sequences &
Gene Models
less
  • All Sequences
    4
  • RefSeq
    2
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic AF017258 GenBank | ENA | DDBJ | MGI Sequence Detail 471 Not Specified ±  kb
transcript NM_017388 RefSeq | MGI Sequence Detail 471 Not Specified  
polypeptide O35290 UniProt | EBI | MGI Sequence Detail 156 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less

  • Microarray probesets 3
References
more
  • Summaries
    All 13
    Gene Ontology 4
  • Earliest
    J:44252 Batten D, et al., Molecular cloning of four novel murine ribonuclease genes: unusual expansion within the ribonuclease A gene family. Nucleic Acids Res. 1997 Nov 1;25(21):4235-9
  • Latest
    J:87791 Dyer KD, et al., Identification of a purine-rich intronic enhancer element in the mouse eosinophil-associated ribonuclease 2 (mEar 2) gene. Mamm Genome. 2004 Mar;15(2):126-34
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory