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Rmp4 QTL Detail
Summary
  • Symbol
    Rmp4
  • Name
    resistance to mousepox 4
  • Feature Type
    QTL
  • IDs
    MGI:104795
    NCBI Gene: 109961
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 1, cM position of peak correlated region/marker: Syntenic
  • Mapping Data
    1 experiment
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
This QTL contributes to differences in resistance to mortality from ectromelia virus infection. C57BL/6 is resistant; DBA/2 is susceptible. Some BXD lines lose resistance upon castration inferring a role for gonadal factors, but castrate C57BL/6 remain resistant indicating a redundant mechanism.
Sequences &
Gene Models
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Other
Accession IDs
less
MGD-MRK-28087
References
more
  • Summaries
    All 2
    Phenotypes 1
  • Earliest
    J:29241 Brownstein DG, et al., Chromosome mapping of Rmp-4, a gonad-dependent gene encoding host resistance to mousepox. J Virol. 1995 Nov;69(11):6958-64

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory